Researcher Database

HIKIRI SIMON

Department / Course College of Life Sciences Department of Bioinformatics

Title / Position Assistant Professor

Papers
1.	2022/10	A methodology for creating mutants of G‐protein coupled receptors stabilized in active state by combining statistical thermodynamics and evolutionary molecular engineering │ Protein Science │ 31 (10),pp.e4425 (Co-authored)
2.	2020/08	Comparison based on statistical thermodynamics between globule-to-coil transition of poly(N-isopropylacrylamide) and cold denaturation of a protein │ Journal of Molecular Liquids │ 317 (1),pp.114129 (Co-authored)
3.	2020/02	Hydration properties of a protein at low and high pressures: Physics of pressure denaturation │ Journal of Chemical Physics │ 152 (6),pp.065103 (Co-authored)
4.	2019/10	Mechanism of globule-to-coil transition of poly(N-isopropylacrylamide) in water: Relevance to cold denaturation of a protein │ Journal of Molecular Liquids │ 292 (15),pp.111374 (Co-authored)
5.	2019/08	How Does the Recently Discovered Peptide MIP Exhibit Much Higher Binding Affinity than an Anticancer Protein p53 for an Oncoprotein MDM2? │ Journal of Chemical Information and Modeling │ 59 (8),pp.3533 (Co-authored)
6.	2019/05	An accurate and rapid method for calculating hydration free energies of a variety of solutes including proteins │ Journal of Chemical Physics │ 150 (17),pp.175101 (Co-authored)
7.	2018/08	Statistical thermodynamics for the unexpectedly large difference between disaccharide stereoisomers in terms of solubility in water │ Physical Chemistry Chemical Physics │ 20 (36),pp.23684 (Co-authored)
8.	2018/04	Physical Origin of Thermostabilization by a Quadruple Mutation for the Adenosine A_2a Receptor in the Active State │ Journal of Physical Chemistry B │ 122 (16),pp.4418 (Co-authored)
9.	2016/12	Computational Methods for Configurational Entropy Using Internal and Cartesian Coordinates │ Journal of Chemical Theory and Computation │ 12 (12),pp.5990 (Co-authored)