研究者学術情報データベース

イズミカワ　トモミ
泉川　友美
IZUMIKAWA TOMOMI

所属薬学部創薬科学科

職名助教

論文
1.	2019	Enhanced hexosamine metabolism drives pro-tumorigenic signaling pathways involving hyaluronan and O-GlcNAcylation in aggressive breast cancer. │ Cell Death & Disease │ 10 (11),803 (共著)
2.	2019	Regulatory Mechanism of 2-O-Phosphorylation of Xylose in the Glycosaminoglycan-Linkage Region of the Tetrasaccharide, │ Trends in Glycoscience and Glycotechnology │ ,E57-E62 (単著)
3.	2019	常染色体劣性骨格異形成症の原因遺伝子であるグリピカン-6のヘッジホッグシグナル伝達制御機構 │ Journal of Japanese Biochemical Society │ ,91, 241-245 (単著)
4.	2018	Metabolic Reprogramming and Hyaluronan Production in Cancer Stem Cells │ Trends in Glycoscience and Glycotechnology │ ,E147-E154 (共著)
5.	2017	Glypican-6 promotes the growth of developing long bones by stimulating Hedgehog signaling │ Journal of Cell Biology │ 216,2911-2926 (共著)
6.	2016	Chondroitin 4-O-Sulfotransferase Is Indispensable for Sulfation of Chondroitin and Plays an Important Role in Maintaining Normal Life Span and Oxidative Stress Responses in Nematodes │ Journal of Biological Chemistry │ 291,23294-23304 (共著)
7.	2016	Chondroitin sulfate β-1,4-N-acetylgalactosaminyltransferase-1 (ChGn-1) polymorphism; association with progression of multiple sclerosis │ Neuroscience Research │ 108,55-59 (共著)
8.	2016	Production Regulates Metabolic and Cancer Stem-like Properties of Breast Cancer Cells via Hexosamine Biosynthetic Pathway-coupled HIF-1 Signaling │ Journal of Biological Chemistry │ 291,24105-24120 (共著)
9.	2015	A sulfated glycosaminoglycan linkage region is a novel type of Human Natural Killer-1 (HNK-1) epitope expressed on aggrecan in perineuronal nets │ PLoS ONE │ 10,e0144560 (共著)
10.	2015	Amino acid sequence surrounding the chondroitin sulfate attachment site of thrombomodulin regulates chondroitin polymerization │ Biochemical and Biophysical Research Communications │ 460,233-237 (共著)
11.	2015	GlcUAβ1-3Galβ1-3Galβ1-4Xyl(2-O-phosphate) is the preferred substrate for chondroitin N-acetylgalactosaminyltransferase-1. │ Journal of Biological Chemistry │ 290,5438-5448 (共著)
12.	2015	Processing by Convertases Is Required for Glypican-3-induced Inhibition of Hedgehog Signaling. │ Journal of Biological Chemistry │ 290,7576-7585 (共著)
13.	2014	Chondroitin Sulfate Is Indispensable for Pluripotency and Differentiation of Mouse Embryonic Stem Cells │ Scientific Reports │ 4,3701 (共著)
14.	2014	Identification of phosphatase that dephosphorylates xylose in the glycosaminoglycan-protein linkage region of proteoglycans │ Journal of Biological Chemistry │ 289,6695-6708 (共著)
15.	2013	A chondroitin synthase-1 (ChSy-1) missense mutation in a patient with neuropathy impairs the elongation of chondroitin sulfate chains initiated by chondroitin N-acetylgalactosaminyltransferase-1. │ Biochimica et Biophysica Acta │ 1830,4806-4812 (共著)
16.	2012	Chondroitin 4-O-sulfotransferase-2 regulates the number of chondroitin sulfate chains initiated by chondroitin N-acetylgalactosaminyltransferase-1 │ Biochemical Journal │ 441,697-705 (共著)
17.	2012	Chondroitin sulfate-E fine-tunes osteoblast differentiation via ERK1/2, Smad3 and Smad1/5/8 signaling by binding to N-cadhrin and cadherin-11 │ Biochemical and Biophysical Research Communications │ 420,523-529 (共著)
18.	2011	Chondroitin 4-O-sulfotransferase-1 regulates the chain length of chondroitin sulfate in cooperation with chondroitin N-acetylgalactosaminyltransferase-2 │ Biochemical Journal │ 434,321-331 (共著)
19.	2011	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase-1 missense mutations are associated with neuropathies │ Journal of Human Genetics │ 56,143-146 (共著)
20.	2011	Correlation of C4ST-1 and CnGn-2 expression with chondroitin sulfate chain elongation in atherosclerosis │ Biochemical and Biophysical Research Communications │ 406,36-41 (共著)
21.	2011	Sulfation of glucuronic acid in the linkage tetrasaccharide by HNK-1 sulfotransferase is an inhibitory signal for the expression of a chondroitin sulfate chain on thrombomodulin │ Biochemical and Biophysical Research Communications │ 415,109-113 (共著)
22.	2010	Chondoroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development │ Biochemical Journal │ 432,47-55 (共著)
23.	2010	Glycosaminoglycans in Development, Health and Disease Mice deficient in glucuronyltransferase-I. │ Elsevier │ ,19-34 (共著)
24.	2010	Impairment of embryonic cell division and glycosaminoglycan biosynthesis in glucuronyltransferase-I-deficient mice │ Journal of Biological Chemistry │ 285,12190-12196 (共著)
25.	2010	Two Golgi-resident 3'-phosphoadenosine 5'-phosphosulfate transporters play distinct roles in heparan sulfate modifications and embryonic and larval development in Caenorhabditis elegans │ Journal of Biological Chemistry │ 285,24717-24728 (共著)
26.	2009	FAM20B is a Kinase that Phosphorylates Xylose in the Glycosaminoglycan-Protein Linkage Region │ Biochemical Journal │ 421,157-162 (共著)
27.	2008	2-O-phosphorylation of xylose and 6-O-sulfation of galactose in the protein linkage region of glycosaminoglycans influence the glucuronyltransferase-I activity involved in the linkage regions synthesis │ Journal of Biological Chemistry │ 283,16801-16807 (共著)
28.	2008	Identification of chondroitin sulfate glucuronyltransferase as chondroitin synthase-3 involved in chondroitin polymerization: Chondroitin polymerization is achieved by multiple enzyme complexes consisting of chondroitin synthase family members │ Journal of Biological Chemistry │ 283,11396-11406 (共著)
29.	2007	Expression of rib-1, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes, is indispensable for heparan sulfate synthesis and embryonic morphogenesis │ Journal of Biological Chemistry │ 282,8533-8544 (共著)
30.	2007	Involvement of chondroitin sulfate synthase-3 (chondroitin synthase-2) in chondroitin polymerization through its interaction with chondroitin synthase-1 or chondroitin polymerizing factor │ Biochemical Journa │ 40,545-552 (共著)
31.	2006	C. elegans pharyngeal morphogenesis requires both de novo synthesis of pyrimidines and synthesis of heparan sulfate proteoglycans │ Developmental Biology │ 296,409-420 (共著)
32.	2006	Chondroitin 4-O-sulfotransferase-1 regulates E disaccharide expression of chondroitin sulfate required for herpes simplex virus infectivity │ Journal of Biological Chemistry │ 281,38668-38674 (共著)
33.	2006	Essential roles of 3'-phosphoadenosine 5'-phoshosulfate synthase in embryonic and larval development of the nematode Caenorhabditis elegans │ Journal of Biological Chemistry │ 281,11431-11440 (共著)
34.	2006	Heparan sulfate polymerization in Drosophila │ Journal of Biological Chemistry │ 281,1929-1934 (共著)
35.	2004	Nematode chondroitin polymerizing factor showing cell/organ-specific expression is indispensable for chondroitin synthesis and embryonic cell division │ Journal of Biological Chemistry │ 279,53755-53761 (共著)
36.	2003	Molecular cloning of a chondroitin polymerizing factor that cooperates with chondroitin synthase for chondroitin polymerization │ Journal of Biological Chemistry │ 278,23666-23671 (共著)