立命館大学 研究者学術情報データベース
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ホソキ ルミコ
細木 るみこ
HOSOKI RUMIKO
所属
薬学部 薬学科
職名
教授
論文
1.
2023
Computer Science Technology in Natural Products Research: A Review of Its Applications and Implications. │ Chem. Pharm. Bull. │ 71 (7),486-494頁
2.
2022
大麻・CBD（カンナビジオール）製品に関する薬学生への意識調査 －実態の把握と学生の意識のテキストマイニング分析－ │ 薬学教育 │ 6
3.
2021/11
Effective Search of Triterpenes with Anti-HSV-1 Activity Using a Classification Model by Logistic Regression. │ Frontiers in chemistry │
4.
2021
Spontaneous and Immune Checkpoint Inhibitor‑Induced Autoimmune Diseases: Analysis of Temporal Information by Using the Japanese Adverse Drug Event Report Database │ Clinical Drug Investigation │ 41 (7),615-627頁
5.
2021
立命館大学におけるレギュラトリーサイエンス教育の事例
－ 医薬品の模擬承認審査 │ 薬学教育 │ 5,333-340頁
6.
2018
A proposal for improving the design of fracture studies involving new drugs for osteoporosis by reducing the number of patients, shortening the administration period, and minimizing disadvantages for patients in the placebo group. │ RSMP │ 8,151-163
7.
2016
PMDAにおけるレギュラトリーサイエンスの取り組み │ 日本薬理学雑誌 │ 148,9-13
8.
2002
新医薬品承認申請において必要とされる薬理学の役割 │ 日本薬理学雑誌 │ 120,187-194
9.
1998
Pharmacological profiles of new orally active nonpeptide tachykinin NK1 receptor antagonists. │ Eur. J. Pharmacol. │ 341,235-241
10.
1997
Enzyme inactivation of enkephalin neurotransmitters in the spinal cord of the neonatal rat. │ Neurosci. Res. │ 28,261-267
11.
1997
Tachykinin receptors on motoneurons in the spinal cords of neonatal rats, gerbils and hamsters. │ Neuropeptides │ 31,495-501
12.
1997
The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide. │ Biochem. Biophys. Res. Commun. │ 237,527-531
13.
1997
受容体はどのように考えられてきたか －薬物受容体機構の変遷を中心に－ │ 薬局 │ 48,4-13
14.
1996
Phenoxybenzamine discriminates between two distinct populations of histamine H1-receptors in longitudinal muscle of guinea-pig ileum. │ J. Smooth Muscle Res. │ 32,249-254
15.
1996
Some pharmacological properties of a newly synthesized 3-acetoxy-6-acetylthio-10-oxo-N-cyclopropylmethyldihydro-normorphine (KT-95). │ Archives int. Pharmacodyn. │ 331,136-152
16.
1995
Pharmacological characterization of GR82334, a tachykinin NK1 receptor antagonists, in the isolated spinal cord of the neonatal rat. │ Eur. J. Pharmacol. │ 281,49-54
17.
1995
Use of NK1 receptor antagonists in the exploration of physiological functions of substance P and neurokinin A. │ Can. J. Physiol. Pharmacol. │ 73,903-907
18.
1994
Effects of RP 67580, a tachykinin NK1 antagonist, on a primary afferent-evoked response of ventral roots in the neonatal rat spinal cord. │ Br. J. Pharmacol. │ 113,1141-1146
19.
1994
Involvement of enzymatic degradation in the inactivation of tachykinin neurotransmitters in neonatal rat spinal cord. │ Br. J. Pharmacol. │ 113,310-316
20.
1993
Depression of primary afferent-evoked responses by GR71251 in the isolated spinal cord of the neonatal rat. │ Br. J. Pharmacol. │ 110,1142-1148
21.
1993
Pharmacological properties of a slow C-fiber response induced by stimulation of greater splanchnic nerve in an isolated spinal cord-nerve preparation of the newborn rat. │ Regulat. Peptides │ 46,285-286
22.
1993
Potentiating effect of peptidase inhibitors on a C fiber-evoked response in the isolated spinal cord preparation of the neonatal rat. │ Regulat. Peptides │ 46,458-460
23.
1992
Enzymatic inactivation of tachykinin neurotransmitters in the isolated spinal cord of the newborn rat. │ Neurosci. Res. │ 15,289-292
24.
1992
Inhibitory effects of human, porcine and rat galanin examined in the isolated spinal cord of the newborn rat. │ Biomedical Res. │ 13 (suppl.2),325-328
25.
1992
The isolated spinal cord-skin preparation of the newborn rat and effects of some algogenic and analgesic substances. │ Eur. J. Pharmacol. │ 220,111-117
26.
1987
Pharmacological evidence for the possible coexistence of multiple receptor sites for mammalian tachykinins in rabbit iris sphincter smooth muscle. │ Naunyn-Schmiedeberg's Arch. Pharmacol. │ 335,290-295
27.
1985
Some characterization of the responses to substance P and other tachykinins in rabbit iris sphincter muscle. │ Japan. J. Pharmacol. │ 37,159-165
28.
1984
Effect of clenbuterol, a new selective adrenoceptor stimulant, on the release of histamine and SRS-A from passively sensitized guinea-pig chopped lungs. │ Gen. Pharmacol. │ 15,345-348
