研究者学術情報データベース

ムカイ　エリ
向　英里
MUKAI ERI

所属生命科学部生命医科学科

職名教授

論文
1.	2026/03	Revisiting leader–member exchange: a review through the lens of the “too much of a good thing” effect │ Frontiers in Psychology │ 17
2.	2023/03	White-skinned sweet potato (Ipomoea batatas L.) acutely suppresses postprandial blood glucose elevation by improving insulin sensitivity in normal rats │ Heliyon │ 9 (4),e14719
3.	2022/09	Role of reactive oxygen species in glucose metabolism disorder in diabetic pancreatic β-cells │ Biomolecules │ 12 (9),1228
4.	2022/02	Bitter melon fruit extract enhances intracellular ATP production and insulin secretion from rat pancreatic β-cells │ British Journal of Nutrition │ 127 (3),377-383頁
5.	2021/12	Development of novel radioiodinated exendin-4 derivatives targeting GLP-1 receptor for detection of β-cell mass. │ Bioorganic & Medicinal Chemistry │ 52,116496
6.	2020/11	Single-Cell Transcriptome Analysis Dissects the Replicating Process of Pancreatic Beta Cells in Partial Pancreatectomy Model. │ iScience │ 23 (12),101774
7.	2020/06	Bitter melon fruit extract has a hypoglycemic effect and reduces hepatic lipid accumulation in ob/ob mice. │ Phytotherapy Research │ 34 (6),1338-1346頁
8.	2020/01	Bitter melon fruit extract affects hepatic expression of the genes involved in inflammation and fatty acid metabolism in ob/ob mice. │ Functional Food s in Health and Disease │ 10 (1),18-36頁
9.	2018/01	Evaluation of 18F-labeled exendin(9-39) derivatives targeting glucagon-like peptide-1 receptor for pancreatic β-cell imaging. │ Bioorganic & Medical Chemistry │ 26 (2),463-469
10.	2016/11	Oral Administration of Apple Procyanidins Ameliorates Insulin Resistance via Suppression of Pro-Inflammatory Cytokine Expression in Liver of Diabetic ob/ob Mice │ Journal of Agriculural Food and Chemistry │ 64 (46),8857-8865
11.	2016/03	Distinct effects of dipeptidyl peptidase-4 inhibitor and glucagon-like peptide-1 receptor agonist on islet morphology and function │ Endocrine │ 51 (3),429-439
12.	2016/03	Src regulates insulin secretion and glucose metabolism by influencing subcellular localization of glucokinase in pancreatic β-cells. │ Journal of Diabetes Investigation │ 7 (2),171-178
13.	2014/09	Enhanced vascular endothelial growth factor signaling in islets contributes to β cell injury and consequential diabetes in spontaneously diabetic Torii rats │ Diabetes Research and Clinical Practice │ 106 (2),303-311
14.	2014/07	Murine insulinoma cell-conditioned medium with BETA2/Neurod1 transduction efficiently induces the differentiation of adipose-derived mesenchymal stem cells into β-like cells both in vitro and in vivo │ Journal of Stem Cell Research & Therapy │ 4 (8),1-9
15.	2014/06	Synthesis and evaluation of (18)F-labeled mitiglinide derivatives as positron emission tomography tracers for β-cell imaging │ Bioorganic & Medical Chemistry │ 22 (13),3270-3278
16.	2014/02	Palmitate induces reactive oxygen species production and β-cell dysfunction by activating nicotinamide adenine dinucleotide phosphate oxidase through Src signaling │ Journal of Diabetes Investigation │ 5 (1),19-26
17.	2013/01	Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproduction │ Diabetes │ 62 (6),1996-2003
18.	2011/11	Role of endogenous ROS production in impaired metabolism-secretion coupling of diabetic pancreatic β cells │ Progress in Biophysics and Molecular Biology │ 107 (2),304-310
19.	2011/08	Three-dimensional ex vivo imaging and analysis of intraportal islet transplants │ Transplant International │ 24 (8),839-844
20.	2011/04	Role of Mitochondrial Phosphate Carrier in Metabolism-Secretion Coupling in Rat Insulinoma Cell Line INS-1 │ Biochemical Journal │ 435 (2),421-430
21.	2011/01	Exendin-4 suppresses SRC activation and reactive oxygen species production in diabetic Goto-Kakizaki rat islets in an Epac-dependent manner │ Diabetes │ 60 (1),218-226
22.	2010/07	Metformin suppresses hepatic gluconeogenesis and lowers fasting blood glucose levels through reactive nitrogen species in mice │ Diabetologia │ 53 (7),1472-1481
23.	2010/05	Exendin-4 protects pancreatic beta cells from the cytotoxic effect of rapamycin by inhibiting JNK and p38 phosphorylation │ Hormone and Metabolic Research │ 42 (5),311-317
24.	2010/01	Rapamycin impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism │ Journal of Endocrinology │ 204 (1),37-46
25.	2009/10	GLP-1 receptor antagonist as a potential probe for pancreatic beta-cell imaging │ Biochemical and Biophysical Research Communications │ 389 (3),523-526
26.	2009/06	Effects of long-term dipeptidyl peptidase-IV inhibition on body composition and glucose tolerance in high fat diet-fed mice │ Life Sciences │ 84 (25-26),876-881
27.	2008/07	Src activation generates reactive oxygen species and impairs metabolism–secretion coupling in diabetic Goto–Kakizaki and ouabain-treated rat pancreatic islets │ Diabetologia │ 51 (7),1226-1235
28.	2008/06	Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles (RLPs) and mediates RLP-induced migration of vascular smooth muscle cells │ Atherosclerosis │ 198 (2),272-279
29.	2008/01	A novel gastric inhibitory polypeptide (GIP) receptor splice variant influences GIP sensitivity of pancreatic β-cells in obese mice │ American Journal of Physiology Endocrinology and Metabolism │ 294 (1),61-68
30.	2007/09	Impaired metabolism-secretion coupling in pancreatic beta-cells: role of determinants of mitochondrial ATP production │ Diabetes Research and Clinical Practice │ 77 (S1),2-10
31.	2007/07	Mulberry leaf aqueous fractions inhibit TNF-alpha-induced nuclear factor kappaB (NF-kappaB) activation and lectin-like oxidized LDL receptor-1 (LOX-1) expression in vascular endothelial cells │ Atherosclerosis │ 193 (1),20-27
32.	2007/05	Efficient gene transfer into murine pancreatic islets using adenovirus vectors │ Journal of Controlled Release │ 119 (1),136-141
33.	2006/06	Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets │ Endocrinology │ 147 (6),2717-2727
34.	2005/09	ATP enhances exocytosis of insulin secretory granules in pancreatic islets under Ca2+-depleted condition │ Diabetes Research and Clinical Practice │ 69 (3),216-223
35.	2005/08	Nestin-positive cells in adult pancreas express amylase and endocrine precursor cells │ Pancreas │ 31 (2),126-131
36.	2005/02	Chronic exposure to β-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents │ American Journal of Physiology Endocrinology and Metabolism │ 288 (2),372-380
37.	2005/02	Tacrolimus suppresses glucose-induced insulin release from pancreatic islets by reducing glucokinase activity │ American Journal of Physiology Endocrinology and Metabolism │ 288 (2),365-371
38.	2004/10	Heparin-binding EGF-like growth factor induces expression of lectin-like oxidized LDL receptor-1 in vascular smooth muscle cells │ Atherosclerosis │ 176 (2),289-296
39.	2004/10	Peroxisome proliferator-activated receptor a ligands activate transcription of lectin-like oxidized low density lipoprotein receptor-1 gene through GC box motif │ Biochemical and Biophysical Research Communications │ 323 (3),1116-1123
40.	2002/08	Ouabain suppresses glucose-induced mitochondrial ATP production and insulin release by generating reactive oxygen species in pancreatic islets │ Diabetes │ 51 (8),2522-2529
41.	2002/04	Normalization of cytoplasmic calcium response in pancreatic β-cells of spontaneously diabetic GK rat by the treatment with T-1095, a specific inhibitor of renal Na+-glucose co-transporters │ Hormone and Metabolic Research │ 34 (4),217-221
42.	2002/01	Prior exposure to high glucose augments depolarization-induced insulin release by mitigating the decline of ATP level in rat islets │ Endocrinology │ 143 (1),213-221
43.	2001/09	Recovery of function and mass of endogenous β-cells in streptozotocin-induced diabetic rats treated with islet transplantation │ Biochemical and Biophysical Research Communications │ 287 (1),104-109
44.	2001/07	Distinct effect of diazoxide on insulin secretion stimulated by protein kinase A and protein kinase C in rat pancreatic islets │ Diabetes Research and Clinical Practice │ 53 (1),9-16
45.	2001/06	Heat shock restores insulin secretion after injury by nitric oxide by maintaining glucokinase activity in rat islets │ Biochemical and Biophysical Research Communications │ 284 (1),20-25
46.	2001/01	A novel glucokinase regulator in pancreatic  cells: precursor of propionyl-CoA carboxylase β subunit interacts with glucokinase and augments its activity │ Journal of Biological Chemistry │ 276 (4),2325-2328
47.	2000/10	Augmentation of basal insulin release from rat islets by preexposure to a high concentration of glucose │ American Journal of Physiology Endocrinology and Metabolism │ 279 (4),927-940
48.	2000/03	The insulinotropic mechanism of the novel hypoglycemic agent JTT-608: direct enhancement of Ca2+ efficacy and increase of Ca2+ influx by phosphodiesterase inhibition │ British Journal of Pharmacology │ 129 (5),901-908
49.	1999/10	An insulinotropic effect of vitamin D analog with increasing intracellular Ca2+ concentration in pancreatic β-cells through nongenomic signal transduction │ Endocrinology │ 140 (10)
50.	1999/05	Nisoldipine improves the impaired erythrocyte deformability correlating with elevated intracellular free calcium-ion concentration and poor glycaemic control in NIDDM │ British Journal of Clinical Pharmacology │ 47 (5),499-506
51.	1998/11	Beneficial effect of long-term combined treatment with voglibose and pioglitazone on pancreatic islet function of genetically diabetic GK rats │ Hormone and Metabolic Research │ 30 (11),673-678
52.	1998/10	The antiarrhythmic agent cibenzoline inhibits KATP channels by binding to Kir6.2 │ Biochemical and Biophysical Research Communications │ 251 (2),477-481
53.	1998/03	The novel insulinotropic mechanism of pimobendan: direct enhancement of the exocytotic process of insulin secretory granules by increased Ca2+ sensitivity in β-cells │ Endocrinology │ 139 (3)
54.	1998/02	Necessity of endogenous GTP derived from glucose-6-phosphate for insulin secretion augmented by glucose under protein kinase A activation │ Biochemical and Biophysical Research Communications │ 243 (1),253-257
55.	1998/01	Metabolic inhibition impairs ATP-sensitive K+ channel block by sulfonylurea in pancreatic β-cells │ American Journal of Physiology │ 274 (Endocrinol and Metab, 37),E38-44