研究者学術情報データベース

ホリ　トシユキ
堀　利行
HORI Toshiyuki

所属生命科学部生命医科学科

職名教授

論文
1.	2019/11	BCR-ABL and Src Family Kinases Induce YAP Tyrosine Phosphorylation Resulting in Survivin and Cyclin D1 Expression in Chronic Myeloid Leukemia Cells │ Blood │ 134 (Issue Supplement 1),5366 (共著)
2.	2019/11	BCR‑ABL induces tyrosine phosphorylation of YAP leading to expression of Survivin and Cyclin D1 in chronic myeloid leukemia cells │ Int. J. Hematol. │ 110 (5),591-598 (共著)
3.	2017	TSLP-activated dendritic cells induce human T follicular helper cell differentiation through OX40-ligand │ J.Exp. Med. │ 14,1529-1546 (共著)
4.	2015	Opposing roles of Dectin-1 expressed on human plasmacytoid dendritic cells and myeloid dendritic cells in Th2 polarization. │ J. Immunol. │ 195 (4),1723-1741 (共著)
5.	2014	Human CD141+ Dendritic Cells Induce CD4+ T Cells To Produce Type 2 Cytokines │ J. Immunol. │ 193 (9),4335-4343 (共著)
6.	2013	The C. elegans Rassf homolog, rasf-1, is functionally associated with rab-39 Rab GTPase in oxidative stress response. │ Genes to Cells │ 18,203-210 (共著)
7.	2011	TSLP fosters human breast cancer tumor development by promoting type 2 inflammation. │ J. Exp. Med. │ 208,479-490 (共著)
8.	2009	Human plasmacytoid dendritic cells express an atrial natriuretic peptide receptor, guanylyl cyclase-A │ Microbiol. Immunol. │ 53,403-411 (共著)
9.	2009	Mycophenolate mofetil combined with tacrolimus and minidose methotrexate after unrelated donor bone marrow transplantation with reduced-intensity conditioning │ Int. J. Hematol. │ 89,538-545 (共著)
10.	2009	The CD70-CD27 interaction during the stimulation withdendritic cells promotes naïve CD4+ T cells to develop into Tcells producing a broad array of immunostimulatory cytokines in humans │ Int. Immunol. │ 21,891-904 (共著)
11.	2008	Growth and differentiation advantages of CD4+ OX40+ T cells from allogeneic hematopoietic stem cell transplantation recipients │ Biol. Blood Marrow Tr. │ 14,268-281 (共著)
12.	2008	Kpm/Lats2 is linked to chemo-sensitivity of leukemic cells through the stabilization of p73 │ Blood │ 112,3856-3866 (共著)
13.	2007	Altered homeostasis of CD4 memory T cells in allogeneic hematopoietic stem cell transplant recipients: chronic graft-versus-host disease enhances T cell differentiation and exhausts central memory T cell pool. │ Biol. Blood Marrow Tr. │ 13,1176-1184 (共著)
14.	2007	Cyclin-dependent kinase-like 5 is a novel target of immunotherapy in adult T cell leukemia │ J. Immunother. │ 30,499-505 (共著)
15.	2007	Disseminated Mycobacterium avium complex infection due to autoantibody to interferon-γ. │ Internal Med. │ 46,1005-1009 (共著)
16.	2007	Involvement of OX40 ligand+ mast cells in chronic GVHD after allogeneic hematopoietic stem cell transplantation │ Bone Marrow Transplant. │ 39 (6),373-376 (共著)
17.	2006	Delineation of immunoregulatory properties of adult T cell leukemia cells │ Int. J. Hematol. │ 84,63-69 (共著)
18.	2006	Functional characterization of OX40 expressed on human CD8+ T cells │ Immunol. Lett. │ 106,27-33 (共著)
19.	2006	Identification of HLA class I-restricted tumor-associated antigens in adult T cell leukemia cells by mass spectrometric analysis │ Exp. Hematol. │ 34,1496-1504 (共著)
20.	2006	IgE-activated mast cells in combination with pro-inflammatory factors induce Th2-promoting dendritic cells │ Int. Immunol. │ 18,1789-1799 (共著)
21.	2006	Type I interferons attenuate T cell activating functions of human mast cells by decreasing TNF-a production and OX40 ligand expression while increasing IL-10 production │ J. Clin. Immunol. │ 26,512-518 (共著)
22.	2005	Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA │ Int. Immunol. │ 17,737-747 (共著)
23.	2005	Introduction of OX40 ligand into lymphoma cells elicits anti-lymphoma immunity in vivo │ Exp. Hematol. │ 33,336-343 (共著)
24.	2005	Nitric oxide inhibits IFN-α production of human plasmacytoid dendritic cells partly via a guanosine 3’,5’-cyclic monophosphate-dependent pathway │ J. Immunol. │ 175,806-812 (共著)
25.	2005	Phenotypic and functional relationship between adult T cell leukemia cells and regulatory T cells │ Leukemia │ 19,482-483 (共著)
26.	2005	Serological identification of adult T-cell leukaemia (ATL)-associated antigens │ Br. J. Haematol. │ 130,382-390 (共著)
27.	2005	TSLP-activated dendritic cells induce inflammatory TH2 response through OX40-ligand: a master switch of interleukin-10 and tumor necrosis factor-α │ J. Exp. Med. │ 202,1213-1223 (共著)
28.	2004	Plasmacytoid Dendritic Cells Regulate Th Cell Responses through OX40 Ligand and Type I IFNs │ J. Immunol. │ 172,4253-4259 (共著)
29.	2004	Retroviral transduction of acute myeloid leukemia-derived dendritic cells with OX40 ligand augments their antigen presenting activity │ Br. J. Haematol. │ 124,454-462 (共著)
30.	2003	Atrial natriuretic peptide polarizes human dendritic cells toward a Th2-promoting phenotype through its receptor guanylyl cyclase-coupled receptor-A │ J. Immunol. │ 170,5869-5875 (共著)
31.	2003	Expression of CD134 and CD134 ligand in lesional and nonlesional psoriatic skin. │ Arch. Dermatol. Res. │ 294,563-566 (共著)
32.	2003	Inhibition of cell growth by conditional expression of kpm, a human homologue of Drosophila warts/lats tumor suppressor │ J. Biol. Chem. │ 278,17609-17614 (共著)
33.	2003	Natural alpha interferon-producing cells respond to human immunodeficiency virus-1 with alpha interferon production and maturation into dendritic cells │ J. Virol. │ 77,3777-3784 (共著)
34.	2003	OX40 signaling is crucial for induction of alloreactive human T cell response │ Immunology │ 109,226-231 (共著)
35.	2002	Myasthenia gravis after bone marrow transplantation treated with mycophenolate mofetil monitored by peripheral blood OX40+ CD4+ T cells │ Eur. J. Hematol. │ 69,318-320 (共著)
36.	2002	OX40 signaling renders adult T cell leukemia cells resistant to Fas-induced apoptosis │ Int. J. Hematol. │ 76,260-266 (共著)
37.	2002	Singnaling of gp34 (OX40 ligand) induces vascular endothelial cells to produce a CC chemokine RANTES/CCL5 │ Immunol. Lett. │ 84,1-7 (共著)
38.	2001	Correlation of peripheral blood OX40+ (CD134+) T cells with chronic graft-versus-host disease in patients who underwent allogeneic hematopoietic stem cell transplantation │ Blood │ 98,3162-3164 (共著)
39.	2001	Replacement of the V3 region of gp120 with SDF-1 preserves the infectivity of T-tropic human immunodeficiency virus type 1 │ J. Virol. │ 75,4258-4267 (共著)
40.	2000	Both amino- and carboxyl-terminal domain of TRAF3 negatively regulate NF-κB activation induced by OX40 signaling │ Biochem. Bioph. Res. Co. │ 272,856-863 (共著)
41.	2000	Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression │ Clin. Cancer Res. │ 6,3530-3535 (共著)
42.	2000	Molecular cloning of a novel human protein kinase, kpm, that is homologous to warts/lats, a Drosophila tumor suppressor │ Oncogene │ 19,3101-3109 (共著)
43.	2000	SDF-1 has costimulatory effects on human T cells: possible involvement of MAP kinases (ERK-2) activation │ Microbiol. Immunol. │ 44,135-141 (共著)
44.	2000	SDF-1 has costimulatory effects on human T cells: possible involvement of MAP kinases (ERK-2) activation. │ Microbiol. Immunol. │ 44,135-141 (共著)
45.	2000	Vascular endothelial cells provide T cells with costimulatory signals via the OX40/gp34 system │ J. Leuk. Biol. │ 68,111-118 (共著)
46.	1999	Identification of an adhesion molecule expressed on adult T cell leukemia cells derived from a patient with gastrointestinal involvement: implication for a possible role of integrin β7 in leukemic cell infiltration into intestinal mucosa. │ J. Clin. Immunol. │ 19,186-193 (共著)
47.	1999	Intracellular signaling of gp34, the OX40 ligand: induction of c-jun and c-fos mRNA expression through gp34 upon binding of its receptor, OX40. │ J. Immunol. │ 163,3007-3011 (共著)
48.	1999	Small amino acid changes in the V3 loop of human immunodeficiency virus type 2 determine the coreceptor usage for CXCR4 and CCR5. │ Virology │ 264,237-243 (共著)
49.	1999	TCR-mediated activation of allergen-specific CD45RO+ memory T lymphocytes results in down-regulation of cell-surface CXCR4 expression and a strongly reduced capacity to migrate in response to stromal cell-derived factor-1. │ Int. Immunnol. │ 11,1451-1462 (共著)
50.	1998	Detection and delineation of CXCR-4 (fusin) as an entry and fusion cofactor for T-tropic HIV-1 by three different monoclonal antibodies. │ J. Immunol. │ 160,180-188 (共著)
51.	1998	Dissociation of ligand-induced internalization of CXCR-4 from its co-receptor activity for HIV-1 Env-mediated membrane fusion. Arch. │ Arch. Virol Res. │ 143,851-861 (共著)
52.	1998	Hemophagocytic syndrome in five patients with Epstein-Barr virus negative B-cell lymphoma. │ Cancer │ 82,1963-1972 (共著)
53.	1998	Human T-cell leukemia virus type 1 Tax protein induces the expression of lymphocyte chemoattractant SDF-1/PBSF. │ Virology │ 241,298-303 (共著)
54.	1998	Interleukin-4 induces functional expression of CXCR-4 on human Th1 and Th2 cells which results in activation of ERK-2 MAP kinase following stimulation of CXCR-4-expressing T cells with SDF-1. │ J. Immunol. │ 160,4153-4157 (共著)
55.	1998	T-tropic human immunodeficiency virus type 1 (HIV-1)-derived V3 loop peptides directly bind to CXCR-4 and inhibit T-tropic HIV-1 infection. │ J. Virol. │ 72,9763-9770 (共著)
56.	1998	The up-regulation of p27Kip1 by rapamycin results in G1 arrest of exponentially growing T cell lines. │ J. Biol. Chem. │ 273,5808-5814 (共著)
57.	1997	ATL-derived factor (ADF)/human thioredoxin prevents apoptosis of lymphoid cells induced by L-cystine and GSH depletion: Possible involvement of thiol-mediated redox regulation in apoptosis caused by pro-oxidant state. │ J. Immunol. │ 158,3108-3117 (共著)
58.	1997	Downregulation of CD1 marks acquisition of functional competence by human thymocytes and defines a control point in a late stage of human T cell development. │ J. Exp. Med. │ 185,141-152 (共著)
59.	1997	Induction of the 2B9 antigen/dipeptidyl peptidase IV/CD26 on human natural killer cells by IL-2, IL-12 or IL-15. │ Immunology │ 91,151-158 (共著)
60.	1997	Localization of OX40/gp34 in inflammatory skin diseases: a clue to elucidate the interaction between activated T cells and endothelial cells in extravasation. │ Arch. Dermatol. Res. │ 289,653-656 (共著)
61.	1997	OX40 expressed on fresh leukemic cells from ATL patients mediates cell adhesion to vascular endothelial cells: implication for the possible involvement of OX40 in leukemic cell infiltration. │ Blood │ 89,2951-2958 (共著)
62.	1996	Alternative binding of p56lck and phosphatidylinositol 3-kinase in T cells by sulfhydryl oxidation: implication of aberrant signaling due to oxidative stress in T lymphocytes. │ Mol. Immunol. │ 33,855-865 (共著)
63.	1996	The human OX40/gp34 system directly mediates adhesion of activated T cells to endothelial cells. │ J. Exp. Med. │ 183,2185-2195 (共著)
64.	1995	Suppression of adult leukemia-derived factor/human thioredoxin induction by FK506 and cyclosporinA: a new mechanism of immune modulation via redox control. │ Int. Immunol. │ 7,985-993 (共著)
65.	1995	Thiol-mediated redox regulation of apoptosis: possible roles of cellular thiols other than glutathion in T cell apoptosis. │ J. Immunol. │ 154,3194-3203 (共著)
66.	1994	Massive thymic hyperplasia: Characterization of a rare mediastinal mass. │ J. Ped. Surg. │ 29,1561-1564 (共著)
67.	1994	Thiol-mediated redox regulation of lymphocyte proliferation: possible involvement of adult T cell leukemia-derived factor and glutathione in transferrin receptor expression. │ J. Immunol. │ 152,5633-5642 (共著)
68.	1993	Identification of human pre-T/NK cell-associated genes. │ J. Immunol. │ 151,5810-5821 (共著)
69.	1993	Redox regulation of p56lck protein tyrosine kinase activity in T cells. │ Oncogene │ 8,3133-3139 (共著)
70.	1993	Soluble CD23 as a sensitive marker for Epstein-Barr virus-related disorders after liver transplantaion. │ Transplantation │ 56,1109-1113 (共著)
71.	1992	Human fetal liver-derived CD7+ CD2low CD3- CD56- clones that express CD3 γ, δ, and ε and proliferate in response to IL-2, IL-3, IL-4, or IL-7: implications for the relationship between T and NK cells. │ Blood │ 80,1270-1278 (共著)
72.	1992	Ontogeny of human natural killer cells: fetal NK cells mediate cytolytic function and express cytoplasmic CD3 ε, δ proteins. │ J. Exp. Med. │ 175,1055-1066 (共著)
73.	1992	Pseudo-high affinity interleukin 2 (IL-2) receptor lacks the third component that is essential for functional IL-2 binding and signaling. │ J. Exp. Med │ 176,1265-1272 (共著)
74.	1991	Clonal analysis of human CD4- CD8- CD3- thymocytes highly purified from postnatal thymus. │ J. Immunol. │ 146,2116-2121 (共著)
75.	1991	Cloning of a novel cell type from human fetal liver expressing cytoplasmic CD3δ and ε but not membrane CD3. │ Int. Immunol. │ 3,353-357 (共著)
76.	1991	Comparative analysis of CD8 expressed on mature CD4+ CD8+ T cell clones cultured with IL-4 and that on CD8+ T cell clones: implication for functional significance of CD8β. │ Int. Immunol. │ 3,737-741 (共著)
77.	1991	Identification of a novel human thymocyte subset with a phenotype of CD3- CD4- CD8α+β- : possible progeny of the CD3- CD4- CD8- subset. │ J. Immunol. │ 146,4078-4084 (共著)
78.	1990	Interleukin-2 receptor β-chain (p70-75) expressed on leukemic cells from adult T cell leukemia patients. │ Jpn. J. Cancer Res. │ 81,902-908 (共著)
79.	1990	Role of α chain-IL-2 complex in the formation of the ternary complex of IL-2 and high-affinity IL-2 receptor. │ Int. Immunol. │ 2,521-530 (共著)
80.	1990	Selective Expression of the p70 subunit of the interleukin-2 receptor on lymphocytes from patients with infectious mononucleosis. │ Blood │ 75,415-420 (共著)
81.	1989	Elevated serum-soluble interleukin-2 receptor (Tac antigen) levels in chronic myelogenous leukemia patients with blastic crisis. │ Blood │ 74,1052-1057 (共著)
82.	1988	Characteristics of the IL-2 receptor expressed on large granular lymphocytes from patients with abnormally expanded large granular lymphocytes: implication of a non-Tac IL-2-binding peptide. │ J. Immunol. │ 140,4199-4203 (共著)
83.	1988	Close association between interleukin 2 receptor mRNA expression and human T cell leukemia/lymphoma virus type I viral RNA expression in short-term cultured leukemic cells from adult T cell leukemia patients. │ J. Clin. Invest. │ 81,52-61 (共著)
84.	1988	Increase in cytoplasmic free calcium concentration initiated by T3 antigen stimulation is impaired in adult T-cell leukemia cells. │ Leuk. Res. │ 12,357-363 (共著)
85.	1988	Leukemic cells from a chronic T-lymphocytic leukemia patient proliferated in response to both interleukin-2 and interleukin-4 without prior stimulation and produced interleukin-2 mRNA with stimulation. │ Blood │ 72,1177-1181 (共著)
86.	1987	Establishment of an interleukin-2 dependent human T cell line from a patient with T cell chronic lymphocytic leukemia who is not infected with human T cell leukemia/lymphoma virus. │ Blood │ 70,1069-1072 (共著)
87.	1986	Dissociation of interleukin-2-mediated cell proliferation and IL-2 receptor upregulation in adult T cell leukemia cells. │ Leuk. Res. │ 10,1447-1453 (共著)
88.	1986	Expression of interleukin-2 receptor on T cell chronic lymphocytic leukemia cells and their response to interleukin-2. │ Blood │ 67,316-321 (共著)
89.	1986	Idiopathic giant cell myocarditis accompanied by asymmetric septal hypertrophy. │ Jpn. Circ. J. │ 51,153-156 (共著)
90.	1985/08/01	Interleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells. │ Journal of Clinical Investigation │ 76 (2),446-453頁 (共著)
91.	1985	Interleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells. │ J. Clin. Invest. │ 76,446-453 (共著)