Researcher Database

TOYODA Hidenao

Department / Course College of Pharmaceutical Sciences Department of Pharmaceutical Sciences

Title / Position Professor

Papers
1.	2024/02	Endogenous chondroitin extends the lifespan and healthspan in C. elegans │ Scientific Reports │ 14,pp.4813 (Co-authored)
2.	2023/09	Chondroitin sulfate is required for follicle epithelial integrity and organ shape maintenance in Drosophila │ Development │ 150 (Co-authored)
3.	2023/04	Regulation of morphogen pathways by a Drosophila chondroitin sulfate proteoglycan Windpipe. │ J. Cell Sci. │ 136,pp.1 (Co-authored)
4.	2023/03	Characterization of novel antibodies that recognize sialylated keratan sulfate and lacto-N-fucopentaose I on human induced pluripotent cells: comparison with existing antibodies. │ Glycobiology │ 33 (2),pp.150-164 (Co-authored)
5.	2021/03	Glycan epitopes on 201B7 human-induced pluripotent stem cells using R-10G and R-17F marker antibodies. │ Biomolecules │ 11 (4),pp.508-521 (Co-authored)
6.	2020/01	Heparan sulfate structure affects autophagy, lifespan, responses to oxidative stress, and cell degeneration in Drosophila parkin mutants │ G3 (Bethesda) │ 10,pp.129-141 (Co-authored)
7.	2019/06	Effects of Cu2+ on conformational change and aggregation of hPrP180-192 with a V180I mutation of the prion protein │ Biochem. Biophys. Res. Commun. │ 514,pp.798-802 (Co-authored)
8.	2019/05	Microdetermination of Sialic Acids in Blood Samples by Hydrophilic Interaction Chromatography Coupled to Post-column Derivatization and Fluorometric Detection. │ Anal. Sci. │ 35,pp.517-520 (Co-authored)
9.	2019/05	The effects of Cu2+ on conformational changes of hPrP180-192 derived from the C-terminal region of prion protein │ Biomed. Res. Trace Elements │ 30,pp.1-8 (Co-authored)
10.	2019/03	Establishment and characterization of Drosophila cell lines mutant for heparan sulfate modifying enzymes │ Glycobiology │ 29,pp.479-489 (Co-authored)
11.	2017/06	Binding specificity of R-10G and TRA-1-60/81, and substrate specificity of keratanase II studied with chemically synthesized oligosaccharides. │ Glycoconj. J. │ 34,pp.789-795 (Co-authored)
12.	2017/06	Characterization of glycoproteins expressing the blood group H type 1 epitope on human induced pluripotent stem (hiPS) cells │ Glycoconj. J. │ 34,pp.779-787 (Co-authored)
13.	2017/04	Podocalyxin as a major pluripotent marker and novel keratan sulfate proteoglycan in human embryonic and induced pluripotent stem cells │ Glycoconj. J. │ 34,pp.139-145 (Co-authored)
14.	2015/08	A cytotoxic antibody recognizing lacto-N-fucopentaose I (LNFP I) on human induced pluripotent stem(hiPS) cells. │ 290,pp.20071-20085 (Co-authored)
15.	2015/06	Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing │ Genes Cells │ 20,pp.521-542 (Co-authored)
16.	2015/01	Generation of rat Induced pluripotent stem cells using a plasmid vector and possible application of a keratan sulfate glycan recognizing antibody in discriminating teratoma formation phenotypes │ Biol. Pharm. Bull. │ 38,pp.127-133 (Co-authored)
17.	2014/11	A novel antibody for keratan sulfate expressed on human iPS/ES cells. │ Glycoscience: Biology and Medicine, Springer. │ ,pp.1457-1464 (Co-authored)
18.	2014/11	Glycosaminoglycans in embryonic and induced pluripotent stem cells. │ Glycoscience: Biology and Medicine, Springer. │ ,pp.1493-1498 (Co-authored)
19.	2013/11	Analysis of Drosophila glucuronyl C-5 epimerase:implications for developmental roles of heparan sulfate sulfation compensation and 2-O sulfated glucuronic acid. │ J.Biol.Chem. │ 288,pp.34384-34393 (Co-authored)
20.	2013/03	A novel antibody for human induced pluripotent stem (hiPS) cells and embryonic stem (ES) cells recognizes a type of keratan sulfate lacking oversulfated structures │ Glycobiology │ 23,pp.322-336 (Co-authored)
21.	2013/03	The role of Drosophila heparan sulfate 6-O-endosulfatase in sulfation compensation. │ J.Biol.Chem. │ 288,pp.6574-6582
22.	2012/02	ZG16p, an animal homologue of β-prism fold plant lectins, interacts with heparan sulfate proteoglycans in pancreatic zymogen granules │ Glycobiology │ 22,pp.258-266 (Co-authored)
23.	2011/03	Microdetermination of hyaluronan in human plasma by high-performance liquid chromatography with a graphitized carbon column and postcolumn fluorometric detection │ J. Chromatogr. B │ 879,pp.950-954 (Co-authored)
24.	2009	The 3'-phosphoadenosine 5'-phosphosulfate transporters, PAPST1 and 2, contribute to the maintenance and differentiation of mouse embryonic stem cells. │ PLoS ONE │ 4,pp.e8262 (Co-authored)
25.	2008	Functional analysis of proteoglycan galactosyltransferase II RNA interference mutant flies │ J. Biol. Chem. │ 283,pp.6076-6084 (Co-authored)
26.	2008	Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells │ J. Biol. Chem. │ 283,pp.3594-3606 (Co-authored)
27.	2007	Drosophila 1,4-N-acetylgalactosaminyltransferase-A synthesizes the LacdiNAc structures on several glycoproteins and glycosphingolipids │ Biochem. Biophys. Res. Commun. │ 354,pp.522-527 (Co-authored)
28.	2007	Glycomics of proteoglycan biosynthesis in murine embryonic stem cell differentiation │ J. Proteome Res. │ 6,pp.4374-4387 (Co-authored)
29.	2007	HPLC determination of chondrosine in mouse blood plasma after intravenous or oral dose │ Biol. Pharm. Bull. │ 30,pp.1365-1368 (Co-authored)
30.	2007	Matrix assisted laser desorption ionization-time of flight mass spectrometry analysis of hyaluronan oligosaccharides │ Anal. Chim. Acta. │ 593,pp.207-213 (Co-authored)
31.	2007	Mosquito heparan sulfate and its potential role in malaria infection and transmission │ J. Biol. Chem. │ 282,pp.25376-25384 (Co-authored)
32.	2007	Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human │ Nature Med. │ 13,pp.1363-1367 (Co-authored)
33.	2007	Reduced sulfation of chondroitin sulfate in thyroglobulin derived from human papillary thyroid carcinomas │ Cancer Sci. │ 98,pp.1577-1581 (Co-authored)
34.	2007	Regulation of heparan sulfate 6-O-sulfation by β-secretase activity │ J. Biol.Chem. │ 282,pp.14942-14951 (Co-authored)
35.	2006	Chondroitin acts in the guidance of gonadal distal tip cells in C. elegans │ Dev. Biol. │ 300,pp.635-646 (Co-authored)
36.	2006	Identification and characterization of a novel Drosophila 3'-phosphoadenosine 5'-phosphosulfate transporter │ J. Biol. Chem. │ 281,pp.28508-28517 (Co-authored)
37.	2005	Characterization of heparan sulfate from the unossified antler of Cervus elaphus │ Carbohydr. Res. │ 340,pp.411-416 (Co-authored)
38.	2005	Distinct functional units of the Golgi complex in Drosophila cells │ Proc. Natl. Acad. Sci. │ 102,pp.13467-13472 (Co-authored)
39.	2005	Structural characterization of human liver heparan sulfate │ Biochim. Biophys.Acta │ 1721,pp.1-8 (Co-authored)
40.	2004	Approach for functional analysis of glycan using RNA interference │ Glycoconj. J. │ 21,pp.63-68 (Co-authored)
41.	2003	Cellular binding of hepatitis C virus envelope glycoprotein E2 requires cell surface heparan sulfate │ J. Biol. Chem. │ 278,pp.41003-41012 (Co-authored)
42.	2003	EXT gene family member rib-2 is essential for embryonic development and heparan sulfate biosynthesis in Caenorhabditis elegans │ Biochem. Biophys. Res. Commun. │ 301,pp.317-23 (Co-authored)
43.	2003	Molecular cloning and identification of 3'-phosphoadenosine 5'-phosphosulfate transporte │ J. Biol. Chem. │ 278,pp.25958-25963 (Co-authored)
44.	2002/12	Effect of chondroitin sulfate on murine splenocytes sensitized with ovalbumin │ Immunol. Lett. │ 84,pp.211-216 (Co-authored)
45.	2002/06	Conductivity detection for molecular mass estimation of per-O-sulfonated glycosaminoglycans separated by high-performance size-exclusion chromatography │ J. Chromatogr. A │ 959,pp.95-102 (Co-authored)
46.	2002/06	Identification, structural analysis and function of hyaluronan in developing fish larvae (leptocephali) │ Comp. Biochem. Physiol. B Biochem. Mol. Biol. │ 132,pp.443-451. (Co-authored)
47.	2002/05	Effect of (1-->3)- and (1-->4)-linkages of fully sulfated polysaccharides on their anticoagulant activity │ Carbohydr. Res. │ 337,pp.925-933 (Co-authored)
48.	2002/03	Pretreatment procedure for the microdetermination of chondroitin sulfate in plasma and urine │ Anal Biochem. │ 302,pp.169-174 (Co-authored)
49.	2001/10	1H nuclear magnetic resonance spectroscopic analysis for determination of glucuronic and iduronic acids in dermatan sulfate, heparin, and heparan sulfate │ Anal. Biochem. │ 297,pp.42-51 (Co-authored)
50.	2001/10	Determination of lipid-bound sulfate by ion chromatography and its application to quantification of sulfolipids from kidneys of various mammalian species │ J. Lipid. Res. │ 42,pp.1604-1608 (Co-authored)
51.	2001/09	Quantitative changes in glycosaminoglycans in the lungs of rats exposed to diesel exhaust │ Toxicology │ 166,pp.119-128 (Co-authored)
52.	2001/09	UDP-sugar transporter implicated in glycosylation and processing of Notch │ Nature Cell Biol. │ 3,pp.816-822 (Co-authored)
53.	2001/08	Analytical method of chondroitin/dermatan sulfates using high performance liquid chromatography/turbo ionspray ionization mass spectrometory. Application to analyses of the tumor tissue sections on glass slides │ Biomed. Chromatogr │ 15,pp.356-362 (Co-authored)
54.	2001/08	Comparison of oligosaccharides derived from salivary mucin of Japanese secretor and non-secretor individuals of blood group type-A │ Glycoconj. J. │ 18,pp.635-640 (Co-authored)
55.	2001/04	Analytical method of heparan sulfates using high performance liquid chromatography turbo-ionspray ionization tandem mass spectrometory │ J. Chromatogr. B │ 754,pp.153-159 (Co-authored)
56.	2001/03	Analytical method for keratan sulfates by high-performance liquid chromatography/turbo-ionspray tandem mass spectrometry │ Anal. Biochem. │ 290,pp.68-73 (Co-authored)
57.	2001/01	Preparation and inhibitory activity on hyaluronidase of fully O-sulfated hyaluro-oligosaccharides │ Glycobiology │ 11,pp.57-64 (Co-authored)
58.	2000/09	sqv-3, -7, and -8, a set of genes affecting morphogenesis in Caenorhabditis elegans, encode enzymes required for glycosaminoglycan biosynthesis │ Proc. Natl. Acad. Sci. │ 97,pp.10838-10843 (Co-authored)
59.	2000/07	Structural analysis of glycosaminoglycans in animals bearing mutations in sugarless, sulfateless, and tout-velu. Drosophila homologues of vertebrate genes encoding glycosaminoglycan biosynthetic enzymes │ J. Biol. Chem. │ 275,pp.21856-2186 (Co-authored)
60.	2000/06	Determination of N-acetyl- and N-glycolylneuraminic acids in gangliosides by combination of neuraminidase hydrolysis and fluorometric high-performance liquid chromatography using a GM3 derivative as an internal standard │ Anal. Biochem. │ 281,pp.193-201 (Co-authored)
61.	2000/01	Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo │ J. Biol. Chem. │ 275,pp.2269-2275 (Co-authored)
62.	1999/12	Preparation and anticoagulant activity of fully O-sulphonated glycosaminoglycans │ Int. J. Biol. Macromol. │ 26 (233-241) (Co-authored)
63.	1999/10	Inhibition of hyaluronidase by fully O-sulfonated glycosaminoglycans │ Arch. Biochem. Biophys. │ 370 (176-182) (Co-authored)
64.	1999/02	Oral absorption and clearance of partially depolymerized fucosyl chondroitin sulfate from sea cucumber │ Thromb. Res. │ 93 (129-135) (Co-authored)
65.	1999/01	Alterations of hairless mouse skin exposed to chronic UV irradiation and its prevention by hydrocortisone │ Photochem. Photobiol. │ 69 (41-46) (Co-authored)
66.	1999/01	Rapid and sensitive analysis of disacchride composition in heparin and heparan sulfate by reversed-phase ion-pair chromatography on a 2 µl porous silica gel column │ J. Chromatogr. A │ 830 (197-201) (Co-authored)
67.	1997/09	Chemical microdetermination of heparin in plasma │ 251,pp.219-226 (Co-authored)
68.	1996/01	High-performance liquid chromatographic analysis of glycosaminoglycan-derived oligosaccharides │ 720,pp.275-293 (Co-authored)
69.	1995/12	Determination of a depolymerized holothurian glycosaminoglycan in plasma after intravenous administration by postcolumn HPLC │ 43,pp.2182-2186 (Co-authored)
70.	1992/02	Study of the measurement of chondroitin sulphates in rabbit plasma and serum │ J. Chromatogr. │ 574,pp.142-145 (Co-authored)
71.	1988	Microdetermination of unsaturated disaccharides produced from chondroitin sulfates in rabbit plasma by high performance liquid chromatography with fluorometric detection. │ Anal. Sci. │ 4 (4),pp.381-384