研究者学術情報データベース

ノマ　アキノリ
野間　昭典
NOMA Akinori

所属総合科学技術研究機構

職名上席研究員

論文
1.	2018/10	『心筋細胞フィジオーム理解のための電子教科書“e-Heart”』の生理学教育教材および研究資材としての活用に向けて　第5回ヒト心室細胞(HuVEC)モデルの刺激頻度依存性 │ 日本生理学会雑誌 │ 80 (4),85-91
2.	2018/09	A new myofilament contraction model with ATP consumption for ventricular cell model │ The Journal of Physiological Sciences │ 68 (5),541-554
3.	2018/07	『心筋細胞フィジオーム理解のための電子教科書“e-Heart”』の生理学教育教材および研究資材としての活用に向けて　第4回ヒト心室細胞(HuVEC)モデルのCa2+誘発Ca2+放出（CICR） │ 日本生理学雑誌 │ 80 (3),58-70
4.	2018/04	『心筋細胞フィジオーム理解のための電子教科書“e-Heart”』の生理学教育教材および研究資材としての活用に向けて第3 回　ヒト心室筋細胞（HuVEC）モデルのCa2+ 動態と遅延後脱分極（DAD）の発生 │ 日本生理学雑誌 │ 80 (2),26-39
5.	2018/01	『心筋細胞フィジオーム理解のための電子教科書“e-Heart”』の生理学教育教材および研究資材としての活用に向けて第 2 回ヒト心室筋細胞（HuVEC）モデルを用いた早期後脱分極（EAD）の再現 │ 日本生理学雑誌 │ 80 (1),3-10
6.	2017/11	『心筋細胞フィジオーム理解のための電子教科書“e-Heart”』の生理学教育教材および研究資材としての活用に向けて第1 回 Visual Studio を用いた包括的ヒト心室筋細胞モデルの実行 │ 日本生理学雑誌 │ 79 (4),64-72
7.	2017/04	Regulation of the glucose supply from capillary to tissue examined by developing a capillary model │ J Physiol Sci. │ 68 (4),355-367
8.	2016/01	Mechanisms underlying the volume regulation of the interstitial fluid by capillaries: a simulation study │ Integrative Medicine Research │ 5 (1),11-21
9.	2015/11	Modeling analysis of inositol 1,4,5-trisphosphate receptor-mediated Ca mobilization under the control of glucagon-like peptide-1 in mouse pancreatic b-cells. │ Am J Physiol Cell Physiol │ 310 (5),C337-47
10.	2015/07	A human ventricular myocyte model with refined representation of excitation-contraction coupling │ Biophys. J │ 109 (2),415-427
11.	2015/03	心臓ペースメーカー細胞のイオン機序について │ 循環器専門医 │ 23 (1),9-17
12.	2014/09	EAD and DAD mechanisms analyzed by developing a new human ventricular cell model │ Progress in Biophysics and Molecular Biology │ 116 (1),11-24
13.	2012	Steady-state solutions of cell volume in a cardiac myocyte model elaborated for membrane excitation, ion homeostasis and Ca2+ dynamics. │ J Theor Biol │ 307,70-81
14.	2011/11	Analyzing electrical activities of pancreatic β cells using mathematical models, │ Prog Biophys Mol Biol. │ 107 (2),265-73
15.	2011/07	Ionic mechanisms and Ca2+ dynamics underlying the glucose response of pancreatic β cells: a simulation study, │ J Gen Physiol │ 138 (1),21-37
16.	2011/07	Time-dependent changes in membrane excitability during glucose-induced bursting activity in pancreatic β cells, │ J Gen Physiol │ 138 (1),39-47
17.	2011/04	Reply to "Letter to the Editor: 'Validating the requirement for beat-to-beat coupling of the Ca2+ clock and M clock in pacemaker cell normal automaticity' │ Am J Physiol Heart Circ Physiol │ 300 (6),H2325-H2326
18.	2011	Minor Contribution of Cytosolic Ca2+ Transients to the PacemakerRhythm in Guinea Pig Sinoatrial Node Cells. │ Am J Physiol Heart Circ Physiol, │ 300 (1),H251-61
19.	2011	Systems Analysis of GLP-1 Receptor Signaling in Pancreatic β-cells. │ Am J Physiol Cell Physiol. │ 138 (1),39-47
20.	2010/10	A, Minor contribution of cytosolic Ca2+ transients to the pacemaker rhythm in guinea pig sinoatrial node cells, │ Am J Physiol Heart Circ Physiol. │ 300,H251-61
21.	2010	Characterization of the cardiac Na+/K+ pump by development of a comprehensive and mechanistic model │ J Theor Biol │ 256 (1),68-77
22.	2010	Characterization of the cardiac Na+/K+ pump by development of a comprehensive and mechanistic model │ J Theor Biol │ 265 (1),68-77
23.	2010	Magnesium gating of cardiac gap junction channels │ Prog Biophys Mol Biol │ 103 (1),102-110
24.	2009	A Novel Method to Quantify Contribution of Channels and Transporters to Membrane Potential Dynamics │ Biophys J. │ 97 (12),3086-94
25.	2009	A Novel Method to Quantify Contribution of Channels and Transporters to Membrane Potential Dynamics, │ Biophys J. │
26.	2009	Development of a model of the Na+/H+ exchanger and its central role in regulation of intracellular pH and Na+ in cardiac myocytes │ Biophys J. │ 97 (10),2674-83
27.	2009	Development of a model of the Na+/H+ exchanger and its central role in regulation of intracellular pH and Na+ in cardiac myocytes, │ Biophys J. │
28.	2009	Modeling the cardiac Na+/H+ exchanger based on major experimental findings, │ Mol Cells. │
29.	2009	Modeling the cardiac Na+/H+ exchanger based on major experimental findings, Mol Cells. │ Mol Cells. │ 28 ((2),),p81-5
30.	2008/12	心筋細胞のシミュレーションとその応用、 │
31.	2008	A new integrated method for analyzing heart mechanics using a cell-hemodynamics -autonomic nerve control coupled model of the cardiovascular system │ Prog Biophys Mol Biol │ 96 (1-3),44-59
32.	2008	A simulation study on the activation of cardiac CaMKII delta-isoform and its regulation by phosphatases │ Biophys J │ 95,2139-49
33.	2008	A simulation study on the activation of cardiac CaMKII delta-isoform and its regulation by phosphatases │ Biophys J │ 95,2139-49
34.	2008	Ionic mechanisms underlying the positive chronotropy induced by beta1-adrenergic stimulation in guinea pig sinoatrial node cells: s simulation study │ J Physiol Sci │ 58,53-65
35.	2008	Ionic mechanisms underlying the positive chronotropy induced by beta1-adrenergic stimulation in guinea pig sinoatrial node cells: s simulation study │ J Physiol Sci │ 58,53-65
36.	2007	Ionic mechanisms of cardiac cell swelling induced by blocking Na+/K+ pump as revealed by experiments and simulation │ J Gen Physiol │ 128,495-507
37.	2007	Ionic mechanisms of cardiac cell swelling induced by blocking Na+/K+ pump as revealed by experiments and simulation │ J Gen Physiol │ 128,495-507
38.	2007	Resistance of Cardiac Cells to NCX Knockout: A Model Study │ Annals of the New York Academy of Sciences │ 1099,306-309
39.	2007	Resistance of Cardiac Cells to NCX Knockout: A Model Study │ Annals of the New York Academy of Sciences │ 1099,306-309
40.	2007	Role of Ca2+ transporters and channels in the cardiac cell volume regulation │ Annals of the New York Academy of Sciences │ 1099,377-382
41.	2007	Role of Ca2+ transporters and channels in the cardiac cell volume regulation │ Annals of the New York Academy of Sciences │ 1099,377-382
42.	2007	Simulation analysis of intracellular Na+ and Cl- homeostasis during beta 1-adrenergic stimulation of cardiac myocyte │ Prog.Biophys Mol Biol │ 96,171-186
43.	2007	Simulation analysis of intracellular Na+ and Cl- homeostasis during beta 1-adrenergic stimulation of cardiac myocyte │ Prog.Biophys Mol Biol │ 96,171-186
44.	2007	The Cross-Bridge Dynamics during Ventricular Contraction Predicted by Coupling the Cardiac Cell Model with a Circulation Model │ J Physiol Sci │ 57,275-285
45.	2007	The Cross-Bridge Dynamics during Ventricular Contraction Predicted by Coupling the Cardiac Cell Model with a Circulation Model │ J Physiol Sci │ 57,275-285
46.	2006	A Simulation Study to Rescue the Na+/Ca2+ Exchanger Knockout Mice │ The Journal of Physiological Sciences │ 56,211-217
47.	2006	Calcium-mediated coupling between mitochondrial substrate dehydrogenation and cardiac workload in single guinea-pig ventricular myocytes │ Journal of Molecular and Cellular Cardiology │ 40,394-404
48.	2006	Modeling the Ca2+ gate on cardiac gap junction channel │ J.Physiol.Sci │ 56,79-85
49.	2006	Modelling Cl- homeostasis and volume regulation of the cardiac cell │ Philos Transact A Math Phys Eng Sci │ 364,1245-1265
50.	2006	simBio: A java package for the development of detailed cell models │ Prog Biophys Mol Biol │ 90,360-377
51.	2006	The Cl- homeostasis and volume regulation of the cardiac cell model │ Philos Transact A Math. Phys. Eng. Sci │ 364 (1-3),1245-1265
52.	2005	Regulation of oxidative phosphorylation in intact mammalian heart in vivo │ Biophysical Chemistry │ 116,145-157
53.	2004	An in silico study of energy metabolism in cardiac excitation-contraction coupling │ Japanese Journal of Physiology │ 54,517-522
54.	2004	simBio：生物学的ダイナミックモデル開発基盤 │ 日本エム・イー学会雑誌(BME) │ 3,11
55.	2004	Simulation of ATP Metabolism in Cardiac Excitation-Contraction Coupling │ Progress in Biophysics and Molecular Biology │ 85,279-299
56.	2004	Two types of spontaneous depolarizations in the interstitial cells freshly prepared from the murine small intestine │ Journal of Physiology │ 599,411-422
57.	2004	Two types of spontaneous depolarizations in the interstitial cells freshly prepared from the murine small intestine. │ J Physiol. │ 55,411-422
58.	2004	細胞・生体機能シミュレーションプロジェクト │ ヒューマンインタフェース学会誌 │ 6,39-44
59.	2004	細胞・生体機能シミュレーションプロジェクト‐数理時空間に生体活動を実現す │ 現代医療 │ 36,1073-1079
60.	2004	創薬研究における細胞機能シミュレーション │ 月刊薬事 │ 46,1257-1264