Researcher Database

（Last updated : 2020-09-29 17:36:04）

IZUMIKAWA TOMOMI

Department / Course College of Pharmaceutical Sciences Department of Pharmaceutical Sciences

Title / Position Assistant Professor

Academic background
1.	2007/03 Degree Acquisition	│ Kobe Pharmaceutical University Doctor of Pharmacy
2.	～2007/03	Doctorial Course │ Graduate School of Pharmaceutical Sciences │ Kobe Pharmaceutical University Graduate School │ Completed

Business career
1.	2019/04/01	Assistant Professor │ Faculty of Pharmaceutical Sciences │ Ritsumeikan University
2.	2016 ～ 2019	Assistant Professor │ Faculty of Life Sciences │ Kyoto Sangyo University
3.	2014 ～ 2016	Postdoctral Fellowship for Research Abroad │ Sunnybrook Research Institute, │ University　of Toronto
4.	2007 ～ 2014	Postdoctoral fellow │ Department of Biochemistry │ Kobe Pharmaceutical University

Research activities
1.		The Japanese Biochemical Society
2.		The Japanese Society of Carbohydrate Research

Qualification and license
1.	2002	license for pharmacist

Subject of research
1.	Biosynthetic mechanism and functional analysis of glycosaminoglycan chains using model animals

Research summary
The function analysis of glycosaminoglycan and application of drug development and regenerative medicine We are focusing on the ultramicroanalysis to investigate the physiological roles of glycosaminoglycans, O- and N-linked sugars.

Present specialized field
Analytical chemistry, Cell biology, Biological pharmacy (Keyword：Glycosaminoglycan, glycosyltransferases, embryonic stem cell, glypican, hedgehog signal, cancer stem cells,)

Papers
1.	2019	Enhanced hexosamine metabolism drives pro-tumorigenic signaling pathways involving hyaluronan and O-GlcNAcylation in aggressive breast cancer. │ Cell Death & Disease │ 10 (11),pp.803 (Co-authored)
2.	2019	Regulatory Mechanism of 2-O-Phosphorylation of Xylose in the Glycosaminoglycan-Linkage Region of the Tetrasaccharide, │ Trends in Glycoscience and Glycotechnology │ ,pp.E57-E62 (Sole-authored)
3.	2018	Metabolic Reprogramming and Hyaluronan Production in Cancer Stem Cells │ Trends in Glycoscience and Glycotechnology │ ,pp.E147-E154 (Co-authored)
4.	2017	Glypican-6 promotes the growth of developing long bones by stimulating Hedgehog signaling │ Journal of Cell Biology │ 216,pp.2911-2926 (Co-authored)
5.	2016	Chondroitin 4-O-Sulfotransferase Is Indispensable for Sulfation of Chondroitin and Plays an Important Role in Maintaining Normal Life Span and Oxidative Stress Responses in Nematodes │ Journal of Biological Chemistry │ 291,pp.23294-23304 (Co-authored)
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Winning science prize
1.	2017/07	the Japanese Society of Carbohydrate Research young scientist award of the Japanese Society of Carbohydrate Research