Researcher Database

（Last updated : 2022-05-19 11:23:44）

YOSHIZAWA TAKUYA

Department / Course College of Life Sciences Department of Biotechnology

Title / Position Lecturer

Other Affiliations
1.	College of Life Sciences Department of Biotechnology
2.	Graduate School of Life Sciences

Academic background
1.	～2012/03	Doctoral Program (1st Semester) │ Department of Nanosystem Science │ Graduate School of Nanobioscience │ Yokohama City University │ Completed
2.	2012/03 Degree Acquisition	│ Yokohama City University Ph.D
3.	～2007/03	Department of Physical Science │ Faculty of Science │ Shinshu University

Research activities
1.		THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN

Research summary
Search for basic mechanism of life phenomena from structural and functional analysis of proteins Just like the visible world, the world of proteins, invisible to our eyes, is filled with diversity. By using methods centered on X-ray crystal structure analysis, to look at the three-dimensional structure of composite protein structure, I wish to elucidate the mechanism of how the proteins cleverly relate with each other and function.

Present specialized field
Structural biochemistry, Biophysics (Keyword：structural biology, X-ray crystallography, biophysics)

Papers
1.	2020/07	Crystal structure of a GH1 β-glucosidase from Hamamotoa singularis. │ Protein science : a publication of the Protein Society │ (Co-authored)
2.	2020	Effect of nuclear import receptors on liquid–liquid phase separation │ (Co-authored)
3.	2019/06	COX6A2 variants cause a muscle-specific cytochrome c oxidase deficiency │ Annals of NEUROLOGY │ 86 (2),pp.193-202 (Co-authored)
4.	2018/04	Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites │ Cell │ 173 (3),pp.693-705, E22 (Co-authored)
5.	2017/11	Structural Basis for the Serratia marcescens Lipase Secretion System: Crystal Structures of the Membrane Fusion Protein and Nucleotide-Binding Domain │ Biochemistry │ 56 (47),pp.6281-6291 (Co-authored)
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