Researcher Database

（Last updated : 2025-08-28 13:06:19）　

TOYODA Hidenao

Department / Course College of Pharmaceutical Sciences Department of Pharmaceutical Sciences

Title / Position Professor

Other Affiliations
1.	Graduate School of Pharmacy
2.	Research Organization of Science and Technology Research Center for Glycobiotechnology

Academic background
1.		Ph.D.
2.	～1988/03	│ Chiba University

Research activities
1.		The Japanese Society for Regenerative Medicine
2.		The Japanese Biochemical Society
3.		The Japanese Society of Carbohydrate Research
4.		The Japan Society for Analytical Chemistry
5.		The Pharmaceutical Society of Japan

Subject of research
1.	(1)Ultra-micro determination of glycoconjugates

Research summary
Ultra-micro determination of glycoconjugates in biological samples We are focusing on the new analytical methods to investigate the physiological roles of glycosaminoglycans, O- and N-linked sugars. =Research theme(1)= Master control glyco-genes for the regulation of cell functions and its application to the drug research.

Present specialized field
Analytical Chemistry (Keyword：Analytical Chemistry Glycobiology)

Books
1.	2021	High-performance liquid chromatography analysis of hyaluronan unsaturated disaccharides
2.	2021	High-performance liquid chromatography analysis of keratan sulfate oligosaccharides

Papers
1.	2024/02	Endogenous chondroitin extends the lifespan and healthspan in C. elegans │ Scientific Reports │ 14,pp.4813
2.	2024/01	In vivo activities of heparan sulfate differentially modified by NDSTs during development. │ Proteoglycan research │ 2 (1)
3.	2023/04	Regulation of morphogen pathways by a Drosophila chondroitin sulfate proteoglycan Windpipe. │ J. Cell Sci. │ 136,pp.1
4.	2023/03	Characterization of novel antibodies that recognize sialylated keratan sulfate and lacto-N-fucopentaose I on human induced pluripotent cells: comparison with existing antibodies. │ Glycobiology │ 33 (2),pp.150-164
5.	2021/03	Glycan epitopes on 201B7 human-induced pluripotent stem cells using R-10G and R-17F marker antibodies. │ Biomolecules │ 11 (4),pp.508-521
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Academic conference presentation
1.	2014/08	Circular dichroism analysis of NFZ peptides derived from TAB2
2.	2010/08	Functional analysis of sulfated glycans in the differentiation of embryonic stem cells.

Message
1.	Analytical sciences in new age For the understanding of cell functions regulated by glycans, it is important to find new genes that direct cooperation working of the glycol-synthetases and to elucidate geneomic information that controls structures of glycans.