Researcher Database

（Last updated : 2024-09-13 08:43:52）

HAYASHI YOSHIHIRO

Department / Course College of Pharmaceutical Sciences Department of Pharmacy

Title / Position Professor

Other Affiliations
1.	Graduate School of Pharmacy

Academic background
1.	2013/03 Degree Acquisition	Doctorial Course │ Graduate School, Division of Medical Sciences │ Shiga University of Medical Science │ Completed
2.	2008/04～2013/03	Doctorial Course │ Graduate School, Division of Medical Sciences │ Shiga University of Medical Science │ Completed

Business career
1.	2023/04 ～	Professor │ │
2.	2020/04 ～ 2023/03	Associate Professor │ │
3.	2017/04 ～ 2020/03	Lecturer │ │

Research activities
1.		The American Society of Hematology

Present specialized field
Pathological biochemistry, Hematology and medical oncology, Tumor biology

Papers
1.	2024/09	IL36G-producing neutrophil-like monocytes promote cachexia in cancer │ Nature Communications │ (Co-authored)
2.	2024/06	HMGA2 promotes platelet-neutrophil complex formation and pulmonary tissue damage in myelodysplastic syndromes │ Blood Vessels, Thrombosis & Hemostasis │ (Co-authored)
3.	2023/04	Mitochondrial dynamics as a pathobiological mediator of clonal myeloid disorders. │ Cancer science │ (Co-authored)
4.	2023/03	The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis. │ Cell reports │ 42 (3),pp.112165 (Co-authored)
5.	2023/01	A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression. │ Nature communications │ 14 (1),pp.23 (Co-authored)
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Academic conference presentation
1.	2020/12	RUNX1 Mutation Leads to Megakaryocyte-Primed Hematopoietic Stem Cell Expansion and Familial Platelet Disorder (The 62nd American Society of Hematology Annual Meeting and Exposition)
2.	2019/12	C/EBPβ Isoforms Regulate Proliferation and Differentiation of Regenerating Hematopoietic Stem/Progenitor Cells (The 61st American Society of Hematology Annual Meeting and Exposition)
3.	2018/12	Inducible Correction of a RUNX1 Mutation of Human AML Causes a Switch of AML to B-ALL (The 60th American Society of Hematology Annual Meeting and Exposition)
4.	2018/12	Mll-Partial Tandem Duplication (Mll-PTD) Causes Pseudohypoxia and Hypermethylation of the Epigenome through Suppression of Mitochondrial Complex II (The 60th American Society of Hematology Annual Meeting and Exposition)
5.	2018/12	Myc Regulates the Development and Anti-Tumor Immunity of Natural Killer Cells (The 60th American Society of Hematology Annual Meeting and Exposition)
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Winning science prize
1.	2017	International Congress on Myelodysplastic Syndromes Tito Bastianello Young Investigator Award
2.	2016	American Society of Hematology Abstract Achievement Award
3.	2015	American Society of Hematology Abstract Achievement Award
4.	2014	American Society of Hematology Abstract Achievement Award
5.	2014	International Society for Experimental Hematology Christa Muller-Sieburg Award
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Grants-in-Aid for Scientific Research -KAKENHI-
1.	2023/04/01 ～ 2026/03/31	Targeting immune cells derived from tumor clones in the pathogenesis of hematological malignancy-related systemic organ failure │ Grant-in-Aid for Scientific Research(B)
2.	2020/04/01 ～ 2022/03/31	Dysregulated mitochondrial dynamics as an underlying mechanism of MDS bone marrow failure │ Early-Career Scientists
3.	2018/04/01 ～ 2020/03/31	Targeting inflammatory polarization of macrophages and cell surface calreticulin in hemophagocytic lymphohistiocytosis │ Early-Career Scientists

Competitive grants, etc. (exc. KAKENHI)
1.	2017	HIF-1α is a central pathobiologic mediator of Myelodysplastic Syndromes │ Research by External Competitive Fund │ 2017 YOUNG INVESTIGATOR GRANT

researchmap Researcher code
B000344691

External Researcher ID
ORCID ID
https://orcid.org/0000-0002-1490-9923