Researcher Database

（Last updated : 2020-09-25 18:59:07）　

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YOSHIKUBO SHIN-ICHI

Department / Course Research Organization of Science and Technology

Title / Position Professor

Academic background
1.	～1989/03	Doctoral Program (2nd Semester) │ Division of Zoology │ Graduate School of Science │ Kyoto University │ Completed Ph.D
2.	～1982/03	Department of Biology │ Faculty of Science │ Tokyo Metropolitan University │ Graduated

Present specialized field
Laboratory animal science, Animal physiology/Animal behavior, Evolutionary biology (Keyword：Primatology, Experimental Psychology, Behavioral Pharmacology (Psychopharmacology), Experimental Zoology)

Papers
1.	2011/11	Discovery of potent, selective, orally active benzoxazepine-based Orexin-2 receptor antagonists │ Bioorganic & Medicinal Chemistry Letters │ 21 (21),pp.6414-6416 (Co-authored)
2.	2011/06	Synthesis of a Novel Series of Tricyclic Dihydrofuran Derivatives: Discovery of 8,9-Dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridines as Melatonin Receptor (MT1/MT2) Ligands │ Journal of Medicinal Chemistry │ 54 (12),pp.4207-4218 (Co-authored)
3.	2009/09	Molecular Cloning and Pharmacological Characterization of Monkey MT1 and MT2 Melatonin Receptors Showing High Affinity for the Agonist Ramelteon │ Journal of Pharmacology and Experimental Therapeutics │ 330 (3),pp.855-863 (Co-authored)
4.	2004/11	Effects of ramelteon (TAK-375) on nocturnal sleep in freely moving monkeys │ Brain Research │ 1027,pp.59-66 (Co-authored)
5.	2002/10	Functional anatomy of chemical senses in the alert monkey revealed by positron emission tomography │ European Journal of Neuroscience │ 16 (5),pp.975-980 (Co-authored)
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